Antigen Background
CD13 antigen, also known as aminopeptidase N, is a member of the type II integral membrane metalloproteases which also includes the leukocyte antigens CD10, CD26, CD73 and BP-1. CD13 antigen is a receptor for the coronaviruses which cause respiratory disease in humans and several animal species. The antigen functions as a zinc-binding metalloprotease which plays a role in cell surface antigen presentation by trimming the N-terminal amino acids from MHC class II-bound peptides. CD13 antigen is reported to be expressed on granulocytes, monocytes and their precursors, most acute myeloid leukemias and a smaller proportion of acute lymphoid leukemias. Non-hematopoietic cells which express CD13 antigen include epithelial cells, renal proximal tubules, intestinal brush border, endothelial cells, fibroblasts, brain cells, bone marrow, osteoclasts and cells lining the bile canaliculi.
| Item Number | Description | |||||
|---|---|---|---|---|---|---|
| PA0304 | CD13 | Details | Request Offer | |||
| Item Number | Description | ||||
|---|---|---|---|---|---|
| Item Number | Description | ||||
|---|---|---|---|---|---|
| name | Type | ||
|---|---|---|---|
| PA0304_MSDS | MSDS | Download | |
